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RStudio metaprop function
Metaprop Function, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/metaprop+function+in/metaprop+function/pm40578863-56-8-5
Average 90 stars, based on 1 article reviews
metaprop function - by Bioz Stars, 2026-09
90/100 stars

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Article Title: p53 major hotspot variants are associated with poorer prognostic features in hereditary cancer patients.
Article Snippet: TP53 pathogenic germline variation is associated with the multi-cancer predisposition Li– Fraumeni syndrome (LFS).. Next-generation sequencing and multigene panel testing are highlighting variability in the clinical presentation of patients with TP53 positive results.. We aimed to investigate if the p53 variants considered as major hotspots at both germline and somatic levels (p.Arg175His, p.Gly245Asp, p.Gly245Ser, p.Arg248Gln, p.Arg248Trp, p.Arg273Cys, p.Arg273His, and p.Arg282Trp) were associated with poorer prognostic features compared to other pathogenic missense variants in the DNA-binding domain.



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